Focal nodular hyperplasia of the liver: a rational approach to treatment

Focal nodular hyperplasia of the liver in a 3 year old child has been successfully treated by ligation of the hepatic artery branches supplying the lesion. The prominence of the abnormal vasculature in the lesion and its possible aetiological involvement is stressed. Because of the risks of partial hepatectomy, hepatic artery ligation is suggested as the treatment of choice for focal nodular hyperplasia.     

Temperature-sensitive mutant of Schizosaccharomyces pombe exhibiting enhanced radiation sensitivity

A conditional lethal and radiation-sensitive mutant of Schizosaccharomyces pombe is described in which both characteristics result from a single gene mutation. Confirmation of the pleiotropic nature of this mutant was obtained by tetrad analysis and by testing the radiation sensitivity of a large number of revertants that grew normally at the restrictive temperature. The colony-forming ability of the mutant after ultraviolet radiation, gamma radiation, and ethyl methane sulfonate treatment is considerably altered by the post-treatment incubation temperature, showing higher survival at 25 than at 30degreesC. The radiosensitivity of the mutant is also influenced by the stage of growth. The difference in radiation sensitivity between the wild type and mutant is greater when log-phase cultures are compared. The characteristics of this mutant suggest that it is defective in a step common to both deoxyribonucleic acid replication and repair.     

Using increased fabrication pressures for making articles from certain electrofused highly refractory materials

Conclusions The porosity of refractories made from fused materials can be greatly reduced (to 10–13%) by using increased fabrication pressures and coarse grained bodies with low quantities of finely milled bond (10–15%).The densification mechanism in the coarse-grained bodies consists in breaking up the large grains and redistributing them. The requirement for maximum density of packing in selecting the grain-size composition of the bodies is of first rate importance.The maximum fabrication pressure should not exceed the values at which the critical density is reached.Translated from Ogneupory No.6, pp.49–53, June, 1972.